Product
Product
TMA - GALILEO CK4500
TMA - GALILEO CK4500
The Galileo TMA CK4500 is the most advanced and fast Galileo Tissue Arrayer model of the family.
*Standard, Macro and Custom cassettes up to 80x120 mm.
*96 well plate format (microtitre of 96/384 wells or eppendorf tube) to be used as support for Nucleic Acids Extractions from the Tissue Cores;
*can be interfaced easily in a Robotic Chain (e.g. Tecan Avio liquid Handling Systems)
*can interface with Commercial Digital Scanners (Aperio, Hamamatsu, TissueGnostics, and others)

HIGH RESOLUTION OPTICS (NAVITAR ZOOM6000 MOUNTED ON A JENOPTIK PROGRES SPEED XT CCD CAMERA)
*Gives the possibility to use the Monitor of the PC to look at the images of the donor blocks, at the glass slide with a good resolution an x20 magification.
*It is used to save the images of the glass slide which can be used later for virtual image sovraimposition and/or to be inserted into the digital report.

 
AUTOMATED AND COMPUTER-GUIDED NEEDLE POSITIONING
The needles are changed and positioned automatically during the TMA construction process to:
*avoid errors that could endanger the TMA quality
*Help the operator in the TMA construction
*speed up the process
*Regulate accurately the punching depth.

 
UP-TO-9 BLOCK AUTOMATED TRAY (PRIOR SCIENTIFIC H138 STAGE)
*Ensure precise positioning of the paraffin blocks under the needles
*Recipient and Donor tissue blocks can be positioned in any of the 6 positions

 
MACRO-BLOCK HOLDER (ONLY FOR GALILEO CK3500 ADVANCED)
*Possibility to mount simultaneously one macro-cassette and up to three standard cassettes on the automated tray
*Use the macro-block both as donor and recipient block

 

1.TEMPLATE EDIT
*Allows the creation of the geometry of the array (paraffin size, needle diameter, number of spots and spacing or pitch between the spots).
*Automatic software check of data inconsistencies or errors.
*Introduce rows/columns or spot groups of spacing to separate the various specimens.
*Automatically centre the array in the recipient block.
*Check the template directly on the recipient block
*Define a library of TMA templates (up to 99 templates) to be re-called and re-used in different TMA projects.

 
2.TMA DESIGN
Define the donor blocks to be used. Donor blocks can be inserted once or added during the work progression.
*Import the donor block codes by using the barcode reader.
*Import the donor block codes from an Excel list.
Link each donor block to one or multiple spots of the TMA.
*Manual spot link
*Linear spot link
*Random spot link
*Automatic design creation
Define up to 8 replicates (depending on the mounted configuration).
*Add a text note for each donor block, recipient block or spot. These notes will be copied in the final report.
*Associate a color code to each spot to improve TMA reading.

 
3.TMA CONSTRUCTION
*Follow the flow chart to proceed with the TMA construction.
*Check the template directly on the recipient block.
*Save all the punch positions for each donor block at the same time. The arrayer will automatically place the blocks during the sampling.
*Check the donor blocks during the sampling phase to avoid mismatching.
*Advance from one step to the next with a simple click of the mouse. All the block movements are automatic.
*Adjust errors and position mismatches in any moment with dedicated functions.
*Complete your array.

 
4.PUNCHING AREA SELECTION:
Manual overlapping:
*Sovraimpose the glass slide on the tissue block
*Align the pre-marked glass slide with the donor block by looking the zoomed images on the LCD color monitor.
*Capture (save) all punch positions using the joystick or with the mouse click.
Digital overlapping
*Capture the glass slide image or import from a file
*Overlap the digitized pre-marked glass slide to the live block image adjusting the transparency as needed.
*Perfectly metch the glass slide image with the live block image (using the stretch image function)
*Capture (save) all punch positions using the joystick or with the mouse click.
*Include glass slide image into the digital report.

 
5.DIGITAL REPORTING
Create the final report of the array on:
Excel spread-sheet:
*Each spot is properly identified during subsequent analysis.
*Relate each spot to the corresponding information.
*Personalize the report, for example adding the results of the analysis or images of the donor blocks and the spots.
Interface with Commercial Digital Scanner
*Create the final TMA report as standard XML TMA description file.
*Interface with other digita scanners (e.g. Aperio, Hamamatsu, TissueGnostics & others)

 
6.QUANTITATIVE DIGITAL PATHOLOGY (VISIOPHARM)
*Automated and fast analysis of tma cores or whole slides
*Accurate detection of tumor cells
*Immediate deployment ensured with ready-to-run image analysis apps
*Build your own image analysis protocols with highly flexible tools
*Run as deployed analysis or pay-as-you-go with cloud analysis
*Fluorescence detection

 

MACRO BLOCK HOLDER
(only for the Galileo CK4500 Advanced)
*Allowes to use one Macro and 3 Standard Tissue Cassettes
*The Macro Block cn be used as donor or recipient
*It is possible to make lage TMA with more than 800 tissue cores

 
1D & 2D BARCODE READER
*Read the barcodes printed on histological cassettes
*Define the donor blocks in the TMA Design phase
*Check the donor blocks during the sampling phase to avoid mismatching

 
WIDE RANGE OF PUNCHING NEEDLE SIZES
*Standard needles: 0.6, 1.0, 1.5 & 2.0 mm
*Special nedles: 3.0 & 5.0 mm (unique feature)